Evidence for the covalent binding of aflatoxin B1-dichloride to cytosine in DNA.

@article{Yu1991EvidenceFT,
  title={Evidence for the covalent binding of aflatoxin B1-dichloride to cytosine in DNA.},
  author={Fu Li Yu and J X Huang and Wanda Bender and Z R Wu and Julia Chin-chu Chang},
  journal={Carcinogenesis},
  year={1991},
  volume={12 6},
  pages={997-1002}
}
In vitro studies of the effect of aflatoxin B1-dichloride (AFB1-Cl2) on the template function for RNA synthesis of several single- and double-stranded synthetic DNAs containing cytosine and/or hypoxanthine bases are reported. The results indicate: (i) AFB1-Cl2 strongly inhibits the template function of the single-stranded homopolymer polydC and has no… CONTINUE READING