Evidence for suppression of immunity as a driver for genomic introgressions and host range expansion in races of Albugo candida, a generalist parasite

@inproceedings{McMullan2015EvidenceFS,
  title={Evidence for suppression of immunity as a driver for genomic introgressions and host range expansion in races of Albugo candida, a generalist parasite},
  author={Mark McMullan and Anastasia Gardiner and Kate Bailey and Eric Kemen and Ben J. Ward and Volkan Çevik and Alexandre Robert-Seilaniantz and Torsten Schultz-Larsen and Alexi L. Balmuth and Eric B. Holub and Cock van Oosterhout and Jonathan D. G. Jones},
  booktitle={eLife},
  year={2015}
}
How generalist parasites with wide host ranges can evolve is a central question in parasite evolution. Albugo candida is an obligate biotrophic parasite that consists of many physiological races that each specialize on distinct Brassicaceae host species. By analyzing genome sequence assemblies of five isolates, we show they represent three races that are genetically diverged by ∼1%. Despite this divergence, their genomes are mosaic-like, with ∼25% being introgressed from other races. Sequential… CONTINUE READING