Evidence for striatal modulation in the presence of fixed cortical injury in obsessive-compulsive disorder (OCD).

@article{Hendler1999EvidenceFS,
  title={Evidence for striatal modulation in the presence of fixed cortical injury in obsessive-compulsive disorder (OCD).},
  author={Talma Hendler and Elinor Goshen and Rina Tadmor and Michal Lustig and Shifra Tzila Zwas and Joseph Zohar},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={1999},
  volume={9 5},
  pages={371-6}
}
A patient with obsessive-compulsive disorder (OCD) onset resulting from a traumatic head injury underwent longitudinal brain imaging evaluation. Structural and functional brain imaging studies were repeatedly performed before and after treatment. Computerized tomography (CT) demonstrated bilateral prefrontal contusions immediately following the trauma and prior to the onset of OCD. Magnetic resonance imaging (MRI) demonstrated bilateral cortical abnormalities in the prefrontal and anterior… CONTINUE READING