Evidence for stretch-induced resistance increase of proximal coronary microcirculation.
@article{Cornelissen2001EvidenceFS,
title={Evidence for stretch-induced resistance increase of proximal coronary microcirculation.},
author={Annemiek J. M. Cornelissen and Jos A. E. Spaan and Jenny Dankelman and C C Chan and Frank Chi-Pong Yin},
journal={American journal of physiology. Heart and circulatory physiology},
year={2001},
volume={281 6},
pages={
H2687-96
}
}We investigated the influence of stretch on regional hemodynamic parameters of the septal circulation. We used a similar experimental setup and mathematical model, as described previously (14). Five ventricular septa were isolated from anesthetized dogs, sutured to a biaxial stretching apparatus, and perfused with an oxygenated perfluorochemical emulsion at maximal vasodilation. Under unloaded and biaxially stretched conditions, flow and septal thickness (to index vascular volume) were measured…
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