Evidence for reset of regulated cortisol in pregnancy: studies in adrenalectomized ewes.

@article{KellerWood1998EvidenceFR,
  title={Evidence for reset of regulated cortisol in pregnancy: studies in adrenalectomized ewes.},
  author={Maureen Keller-Wood},
  journal={The American journal of physiology},
  year={1998},
  volume={274 1 Pt 2},
  pages={R145-51}
}
These studies test the hypothesis that the increased adrenocorticotropic hormone (ACTH) and cortisol in pregnancy reflect a reset of regulated plasma cortisol concentrations. Ewes were sham operated (Sham) or adrenalectomized (ADX) at approximately 108 days gestation. Adrenalectomized ewes were replaced with aldosterone (3 micrograms.kg-1.day-1) and with cortisol at either of two doses (ADX + 0.6 and ADX + 1.0 mg.kg-1.day-1); the ewes were also studied postpartum. Plasma cortisol concentrations… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 36 references

The influence of ovarian steroids on hypothalmic-pituitary-adrenal regulation in the rat

  • M. P. Carey, C. H. Deterd, J. de Koning, F. Helmerhorst, E. R. de Kloet
  • J. Endocrinol
  • 1995
2 Excerpts

Function of the fetal pituitary-adrenal system

  • C. E. Wood
  • Textbook of Fetal Physiology,
  • 1994
1 Excerpt

Similar Papers

Loading similar papers…