Evidence for positive selection in foot-and-mouth disease virus capsid genes from field isolates.

@article{Haydon2001EvidenceFP,
  title={Evidence for positive selection in foot-and-mouth disease virus capsid genes from field isolates.},
  author={Daniel T. Haydon and Armanda D. S. Bastos and Nick J. Knowles and Alan Samuel},
  journal={Genetics},
  year={2001},
  volume={157 1},
  pages={7-15}
}
The nature of selection on capsid genes of foot-and-mouth disease virus (FMDV) was characterized by examining the ratio of nonsynonymous to synonymous substitutions in 11 data sets of sequences obtained from six different serotypes of FMDV. Using a method of analysis that assigns each codon position to one of a number of estimated values of nonsynonymous to synonymous ratio, significant evidence of positive selection was identified in 5 data sets, operating at 1-7% of codon positions. Evidence… CONTINUE READING

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