Evidence for partial exocrine acinar differentiation in experimentally induced pancreatic ductal/ductular cell tumors.

The pancreatic carcinomas induced in Syrian hamsters by a nitroso compound are of a ductal/ductular cell type. Electron microscopic examination of such tumors has revealed the presence of an occasional isolated acinar cell within the tumor. Based on their cellular characteristics, these acinar cells seem to have derived from ductular cell precursors. When… (More)