Evidence for numerous brown adipocytes lacking functional beta 3-adrenoceptors in fat pads from nonhuman primates.

@article{ViguerieBascands1996EvidenceFN,
  title={Evidence for numerous brown adipocytes lacking functional beta 3-adrenoceptors in fat pads from nonhuman primates.},
  author={N. Viguerie-Bascands and Alain Bousquet-M{\'e}lou and Jean Galitzky and Dominique Larrouy and Daniel Ricquier and Michel Berlan and Louis Casteilla},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1996},
  volume={81 1},
  pages={
          368-75
        }
}
Brown adipose tissue (BAT) is involved in the control of energy balance and has been demonstrated to be activated through beta 3-adrenoceptor (beta 3-AR) occupation in rodents. The ability to specifically activate energy expenditure via this receptor is of great interest for the treatment of obesity. Nevertheless, the extent of BAT and the presence of a functional beta 3-AR in humans are now debated, and this situation is difficult to clarify for evident practical and ethical reasons. We… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

PPARs and Adipose Cell Plasticity

VIEW 1 EXCERPT
CITES BACKGROUND

Regulation of body weight in humans.

  • Physiological reviews
  • 1999
VIEW 1 EXCERPT
CITES BACKGROUND

Alpha 2 mu, alpha 2u, or alpha 2u.

  • Environmental health perspectives
  • 1997
VIEW 1 EXCERPT
CITES BACKGROUND