Evidence for novel fate of Flk1+ progenitor: contribution to muscle lineage.

@article{Motoike2003EvidenceFN,
  title={Evidence for novel fate of Flk1+ progenitor: contribution to muscle lineage.},
  author={Toshiyuki Motoike and David W Markham and Janet Rossant and Thomas N Sato},
  journal={Genesis},
  year={2003},
  volume={35 3},
  pages={153-9}
}
Flk1 is one of the specific cell surface receptors for vascular endothelial growth factor and one of the most specific markers highlighting the earliest stage of hematopoietic and vascular lineages. However, recent new evidence suggests that these Flk1(+) mesodermal progenitor cells also contribute to muscle lineages. All evidence is based on the experiments using in vitro differentiation and in vivo transplantation systems. Although this approach revealed a differentiation potential range of… CONTINUE READING

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