• Corpus ID: 17010023

Evidence for nootropic effect of BR-16A (Mentat), a herbal psychotropic preparation, in mice.

  title={Evidence for nootropic effect of BR-16A (Mentat), a herbal psychotropic preparation, in mice.},
  author={Shrinivas Krishnarao Kulkarni and Anita Kamra Verma},
  journal={Indian journal of physiology and pharmacology},
  volume={36 1},
  • S. KulkarniA. Verma
  • Published 1992
  • Biology, Psychology, Chemistry
  • Indian journal of physiology and pharmacology
BR-16A (Mentat 50-500 mg/kg) improved acquisition and retention of a passive avoidance task in a step-down paradigm in mice. BR-16A (50-500 mg/kg) reversed scopolamine (0.3 mg/kg)-induced disruption of acquisition and retention. BR 16-A (50 and 100 mg/kg) attenuated amnesia produced by the acute treatment with electroconvulsive shock (ECS), immediately after training. Chronic treatment with ECS, for 6 successive days at 24 h interval, disrupted memory consolidation on the 7th day. Daily… 

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