Evidence for mitochondrial genetic control of autosomal gene expression.

@article{Kassam2016EvidenceFM,
  title={Evidence for mitochondrial genetic control of autosomal gene expression.},
  author={Irfahan Kassam and Tuan Qi and Luke R. Lloyd-Jones and Alexander Holloway and Marc Jan Bonder and Anjali K. Henders and Nicholas G. Martin and Joseph E. Powell and Lude Franke and Grant W. Montgomery and Peter M. Visscher and Allan F. McRae},
  journal={Human molecular genetics},
  year={2016},
  volume={25 24},
  pages={
          5332-5338
        }
}
The mitochondrial and nuclear genomes coordinate and co-evolve in eukaryotes in order to adapt to environmental changes. Variation in the mitochondrial genome is capable of affecting expression of genes on the nuclear genome. Sex-specific mitochondrial genetic control of gene expression has been demonstrated in Drosophila melanogaster, where males were found to drive most of the total variation in gene expression. This has potential implications for male-related health and disease resulting… 

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