Evidence for microRNA involvement in exercise-associated neutrophil gene expression changes.

@article{RadomAizik2010EvidenceFM,
  title={Evidence for microRNA involvement in exercise-associated neutrophil gene expression changes.},
  author={Shlomit Radom-Aizik and Frank P. Zaldivar and S. Ron Oliver and Pietro Renato Galassetti and Dan M. Cooper},
  journal={Journal of applied physiology},
  year={2010},
  volume={109 1},
  pages={
          252-61
        }
}
Exercise leads to a rapid change in the profile of gene expression in circulating neutrophils. MicroRNAs (miRNAs) have been discovered to play important roles in immune function and often act to attenuate or silence gene translation. We hypothesized that miRNA expression in circulating neutrophils would be affected by brief exercise. Eleven healthy men (19-30 yr old) performed 10, 2-min bouts of cycle ergometer exercise interspersed with 1-min rest at a constant work equivalent to approximately… CONTINUE READING