Evidence for insulin suppression of baseline luteinizing hormone in women with polycystic ovarian syndrome and normal women.

@article{Lawson2008EvidenceFI,
  title={Evidence for insulin suppression of baseline luteinizing hormone in women with polycystic ovarian syndrome and normal women.},
  author={Mark A. Lawson and Sonia Jain and Shelly Sun and Ketan R Patel and Pamela J Malcolm and Russell Jeffrey Chang},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2008},
  volume={93 6},
  pages={2089-96}
}
CONTEXT In women with polycystic ovarian syndrome (PCOS), the relationship of insulin to LH secretion and responses to GnRH remains unresolved. A rigorous analytical examination of this relationship has not been performed. OBJECTIVE Our objective was to determine the relationship of basal LH secretion and responses to GnRH, insulin, and other endocrine variables in normal and PCOS women. DESIGN In PCOS and normal women, mean composite 12-h LH secretion was analyzed for correlating factors… CONTINUE READING

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