Evidence for insertion of a new intron into an Mhc gene of perch-like fish.

@article{Figueroa1995EvidenceFI,
  title={Evidence for insertion of a new intron into an Mhc gene of perch-like fish.},
  author={Felipe Figueroa and Hideki Ono and Herbert Tichy and Colm O'huigin and Jan Klein},
  journal={Proceedings. Biological sciences},
  year={1995},
  volume={259 1356},
  pages={
          325-30
        }
}
The evolution of the major histocompatibility complex (Mhc) has been studied to understand the origin of the immune system, of which it constitutes an essential part. In the present study, the Mhc is used to shed light on questions regarding the origin of introns and the phylogeny of fishes. The organization of the coding (exon) and non-coding (intron) regions of both class I and class II major histocompatibility complex (Mhc) genes is highly conserved in all vertebrate classes; the only… CONTINUE READING

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