Evidence for impaired activation of the hypothalamic-pituitary-adrenal axis in patients with chronic fatigue syndrome.

@article{Demitrack1991EvidenceFI,
  title={Evidence for impaired activation of the hypothalamic-pituitary-adrenal axis in patients with chronic fatigue syndrome.},
  author={Mark A. Demitrack and Janet K. Dale and Stephen E. Straus and Louisa Laue and Samuel J Listwak and Markus J P Kruesi and George P. Chrousos and Philip W. Gold},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1991},
  volume={73 6},
  pages={1224-34}
}
Chronic fatigue syndrome is characterized by persistent or relapsing debilitating fatigue for at least 6 months in the absence of a medical diagnosis that would explain the clinical presentation. Because primary glucocorticoid deficiency states and affective disorders putatively associated with a deficiency of the arousal-producing neuropeptide CRH can be associated with similar symptoms, we report here a study of the functional integrity of the various components of the hypothalamic-pituitary… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 160 extracted citations

Similar Papers

Loading similar papers…