Evidence for heterogeneity of ribosomes within the HeLa cell.

  title={Evidence for heterogeneity of ribosomes within the HeLa cell.},
  author={Edwin H. McConkey and E J Hauber},
  journal={The Journal of biological chemistry},
  volume={250 4},
The proteins of several subsets of ribosomal subunits isolated from HeLa cells were separated by high resolution electrophoresis in polyacrylamide slab gels containing sodium dodecyl sulfate. Comparisons were made among native subunits, and subunits derived from single ribosomes, free polysomes, and membrane-bound polysomes. At least 10 heterogeneously distributed proteins were identified among the 40 S subunit proteins, compared wtih 17 to 20 proteins that occurred in all 40 S subunit classes… CONTINUE READING