Evidence for heterogeneity of hepatic bile salt sulfotransferases in female hamsters and rats.

Gel filtration and anion-exchange chromatography have been used to investigate whether 3'-phosphoadenylylsulfate:bile salt sulfotransferase activity from female rat and hamster liver is heterogeneous. Using these techniques at least three different enzyme activities were demonstrated with two different bile salt substrates. In both animals, but particularly… CONTINUE READING