Evidence for giant linear plasmids in the ascomycete Podospora anserina

  title={Evidence for giant linear plasmids in the ascomycete Podospora anserina},
  author={Josef Hermanns and Anita Asseburg and Heinz D. Osiewacz},
  journal={Current Genetics},
In the extrachromosomal mutant AL2 of the ascomycete Podospora anserina longevity is correlated with the presence of the linear mitochondrial plasmid pAL2-1. In addition to this autonomous genetic element, two types of closely related pAL2-1-homologous molecules were detected in the high-molecular-weight mitochondrial DNA (mtDNA). One of these molecules is of linear and the other of circular structure. Both molecules contain pAL2-1 sequences which appear to be integrated at the same site in the… CONTINUE READING
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