Evidence for fixed charge in the nexus

@article{Brink1980EvidenceFF,
  title={Evidence for fixed charge in the nexus},
  author={Peter R. Brink and Maynard M. Dewey},
  journal={Nature},
  year={1980},
  volume={285},
  pages={101-102}
}
The nexus or gap junction has been characterized as a low-resistance junction as well as a highly permeable junctional membrane to many molecules1–6. The transfer of electrical current from one cell interior to another, the aqueous solubility of dyes used to trace cell to cell communication and the fact that these molecules move across the nexus more rapidly than the plasma membrane4–10 have led to the hypothesis of an aqueous channel in the junction. Both Ca2+ (ref. 11) and H+ (ref. 12) are… CONTINUE READING

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