Evidence for expression of vasopressin V2 receptor mRNA in human lung

@article{Fay1996EvidenceFE,
  title={Evidence for expression of vasopressin V2 receptor mRNA in human lung},
  author={Michael J Fay and Jinlin Du and Xiaoming Yu and William G. North},
  journal={Peptides},
  year={1996},
  volume={17},
  pages={477-481}
}
Studies using fetal sheep, goats, and guinea pigs indicate that vasopressin may play a role in preparing the fetal lung for the transition from a uterine to an air-breathing environment by slowing lung liquid secretion. The mechanism of vasopressin action is believed to occur through V2 receptors with subsequent activation of amiloride-sensitive sodium channels. However, the presence of the V2 receptor in human lung has not yet been documented. In the present study, expression of the… Expand
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  • W. North
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  • Experimental physiology
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TLDR
The results first demonstrated the extrarenal expression of vasopressin V2 receptor in the newborn rat brain, and showed that expressions of vaso-V2 receptor mRNA transcripts are dynamically altered in the process of development. Expand
Molecular cloning and functional expression of a cDNA encoding the human V1b vasopressin receptor.
TLDR
Northern blot analysis revealed that the receptor expression is restricted to the pituitary, and molecular cloning and functional expression of a complementary DNA encoding the human V1b receptor are reported, indicating that the cloned cDNA encodes the V1B receptor. Expand
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The data show that the clone HV-RACE encodes a human vascular-type vasopressin receptor cDNA, which shows a strong sequence homology to the previously cloned rat V1A vasopressingin receptor. Expand
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Cloning and characterization of a vasopressin V2 receptor and possible link to nephrogenic diabetes insipidus
TLDR
The cloning of the rat kidney V2 AVP receptor complementary DNA that encodes a 370-amino-acid protein with a transmembrane topography characteristic of G protein-coupled receptors, and with similarity to the Via (hepatic) AVP receptors2 in its seven membrane-spanning domains is reported. Expand
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TLDR
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TLDR
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Arginine Vasopressin and Atrial Natriuretic Peptide Do Not Alter Ion Transport by Cultured Fetal Distal Lung Epithelium
TLDR
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TLDR
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