Evidence for evolutionary constraints in Drosophila metal biology

@article{Sadraie2011EvidenceFE,
  title={Evidence for evolutionary constraints in Drosophila metal biology},
  author={Maryam Sadraie and Fanis Missirlis},
  journal={BioMetals},
  year={2011},
  volume={24},
  pages={679-686}
}
Mutations in single Drosophila melanogaster genes can alter total body metal accumulation. We therefore asked whether evolutionary constraints maintain biologically abundant metal ions (iron, copper, manganese and zinc) to similar concentrations in different species of Drosophilidae, or whether metal homeostasis is a highly adaptable trait as shown previously for triglyceride and glycogen storage. To avoid dietary influences, only species able to grow and reproduce on a standard laboratory… CONTINUE READING
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