Evidence for eviction and rapid deposition of histones upon transcriptional elongation by RNA polymerase II.

Abstract

Biochemical experiments indicate that transcriptional elongation by RNA polymerase II (Pol II) is inhibited by nucleosomes and hence requires chromatin-modifying activities. Here, we examine the fate of histones upon passage of elongating Pol II in vivo. Histone density throughout the entire Saccharomyces cerevisiae GAL10 coding region is inversely… (More)

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@article{Schwabish2004EvidenceFE, title={Evidence for eviction and rapid deposition of histones upon transcriptional elongation by RNA polymerase II.}, author={Marc A Schwabish and K. Struhl}, journal={Molecular and cellular biology}, year={2004}, volume={24 23}, pages={10111-7} }