Evidence for differentiation in medulloblastomas appearing primitive on light microscopy: an ultrastructural study.


Surgical biopsy specimens from five children with cerebellar medulloblastoma were examined for ultrastructural evidence of differentiating activity. At light microscope level, all the tumour samples appeared primitive and featureless, and could not be classified as showing either neuroblastic or spongioblastic differentiation. Using electron microscopy, the… (More)



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