Evidence for developmental precursor lesions in epilepsy-associated glioneuronal tumors.

@article{Blmcke1999EvidenceFD,
  title={Evidence for developmental precursor lesions in epilepsy-associated glioneuronal tumors.},
  author={Ingmar Bl{\"u}mcke and M L{\"o}bach and Helmut K. Wolf and Otmar Dieter Wiestler},
  journal={Microscopy research and technique},
  year={1999},
  volume={46 1},
  pages={53-8}
}
The etiology and pathogenesis of epilepsy-associated local lesions remain largely unknown. Histopathologically, the most frequent lesions comprise gangliogliomas and glioneuronal malformations, i.e., hamartias or hamartomas, with a preferred location in the temporal lobe of young patients. A characteristic histopathological admixture of glial and neuronal elements, the focal appearance and the benign clinical behaviour suggest a malformative nature. So far, no molecular genetic alterations… CONTINUE READING

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