Evidence for determinism in ventricular fibrillation.
@article{Witkowski1995EvidenceFD, title={Evidence for determinism in ventricular fibrillation.}, author={Witkowski and Kavanagh and Penkoske and Plonsey and Span{\`o} and Ditto and Kaplan}, journal={Physical review letters}, year={1995}, volume={75 6}, pages={ 1230-1233 } }
Using a recently formulated technique for in vivo cardiac transmembrane current estimation, we examined ventricular fibrillation for evidence of deterministic linear and nonlinear structure. Both unstable fixed point analysis and a newly formulated measure of nonlinear determinism indicated that ventricular fibrillation in vivo exhibits deterministic dynamics similar to those previously used in chaos control.
77 Citations
Control of Human Atrial Fibrillation
- MedicineInt. J. Bifurc. Chaos
- 2000
Results are presented on the application and evaluation of chaos control for slowing and regularizing local electrical activation of the right atrium of humans during induced atrial fibrillation.
Quasiperiodicity and chaos in cardiac fibrillation.
- MedicineThe Journal of clinical investigation
- 1997
Evidence indicated that fibrillation arose through a quasiperiodic stage of period and amplitude modulation, thus exemplifying the "quasiperio-temporal chaos" first suggested by Ruelle and Takens.
Spatiotemporal complexity of ventricular fibrillation revealed by tissue mass reduction in isolated swine right ventricle. Further evidence for the quasiperiodic route to chaos hypothesis.
- BiologyThe Journal of clinical investigation
- 1997
A decrease in the number of wave fronts in ventricular fibrillation by tissue mass reduction causes a transition from chaotic to periodic dynamics via the quasiperiodic route.
Chaos and the transition to ventricular fibrillation: a new approach to antiarrhythmic drug evaluation.
- BiologyCirculation
- 1999
Evidence is summarized that the transition from tachycardia to fibrillation is a transition to spatiotemporal chaos, with similarities to the quasiperiodic transition to chaos seen in fluid turbulence, which will support a new paradigm for antiarrhythmic drug classification.
Extraction of physiological and clinical information from intra-atrial electrograms during atrial fibrillation: review of methods.
- MedicineAnnali dell'Istituto superiore di sanita
- 2001
This paper presents a review of the evolution of methods and algorithms for the analysis of intra-atrial recordings, with special emphasis to the extraction of physiological and clinical information…
Ionic Channels and Fibrillation
- Medicine
- 2002
Understanding the mechanisms underlying fibrillation of the heart is very critical as it is the most important cause of stroke in industrialized society.
Deterministic patterns and coupling of bipolar recordings from the right atrium.
- Computer ScienceAnnali dell'Istituto superiore di sanita
- 2001
The detection of spatio-temporal recurrent patterns and of non linear coupling together with the surrogate data results indicate that during atrial fibrillation a certain degree of local organization exists, likely caused by deterministic mechanisms of activation.
STABILITY ANALYSIS OF VENTRICULAR TACHYCARDIA USING DISCRETE
- Medicine
- 1997
Preliminary results indicate that this method may be useful in quantifying the stability of cardiac rhythms, and the degree of determinism.
Stability analysis of ventricular tachycardia using discrete dynamic models
- MedicineProceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)
- 1997
Preliminary results indicate that this method may be useful in quantifying the stability of cardiac rhythms, and the degree of determinism.
References
SHOWING 1-10 OF 17 REFERENCES
Physica (Amsterdam) 73D
- 38
- 1994
Physica (Amsterdam) 58D
- 77
- 1992
Mathematical approaches to cardiac arrhythmias.
- MedicineAnnals of the New York Academy of Sciences
- 1990
Nature (London)363
- 411
- 1993
Physica (Amsterdam) 19D
- 282
- 1986
inMathematical Approaches to Cardiac Arrhythmias
- edited by J. Jalife
- 1990
Phys
- Rev. Lett. 64, 1196
- 1990
Science 214
- 1350
- 1981
Circ
- Res. 72, 424
- 1993
Nature (London) 370
- 615
- 1994