Evidence for determinism in ventricular fibrillation.

@article{Witkowski1995EvidenceFD,
  title={Evidence for determinism in ventricular fibrillation.},
  author={Witkowski and Kavanagh and Penkoske and Plonsey and Span{\`o} and Ditto and Kaplan},
  journal={Physical review letters},
  year={1995},
  volume={75 6},
  pages={
          1230-1233
        }
}
Using a recently formulated technique for in vivo cardiac transmembrane current estimation, we examined ventricular fibrillation for evidence of deterministic linear and nonlinear structure. Both unstable fixed point analysis and a newly formulated measure of nonlinear determinism indicated that ventricular fibrillation in vivo exhibits deterministic dynamics similar to those previously used in chaos control. 
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77 Citations
Background Citations
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Methods Citations
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...

References

SHOWING 1-10 OF 17 REFERENCES

Physica (Amsterdam) 73D

  • 38
  • 1994

Physica (Amsterdam) 58D

  • 77
  • 1992

Mathematical approaches to cardiac arrhythmias.

  • J. Jalife
  • Medicine
    Annals of the New York Academy of Sciences
  • 1990

Nature (London)363

  • 411
  • 1993

Physica (Amsterdam) 19D

  • 282
  • 1986

inMathematical Approaches to Cardiac Arrhythmias

  • edited by J. Jalife
  • 1990

Phys

  • Rev. Lett. 64, 1196
  • 1990

Science 214

  • 1350
  • 1981

Circ

  • Res. 72, 424
  • 1993

Nature (London) 370

  • 615
  • 1994