Evidence for cyclooxygenase activation by nitric oxide in astrocytes.

Abstract

We have evaluated the role of nitric oxide (NO) on the cyclooxygenase pathway in mouse glial cells. Exposure of primary cultures of neonatal mouse cortical astrocytes to bacterial lipopolysaccharide (LPS; 1 microgram/ml, 18 h) caused an increase in the release of both nitrite (NO2-) and prostaglandin E2 (PGE2), products of NO synthase (NOS) and… (More)

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Cite this paper

@article{MolinaHolgado1995EvidenceFC, title={Evidence for cyclooxygenase activation by nitric oxide in astrocytes.}, author={Francisco Molina-Holgado and Ana Lled{\'o} and Camen Guaza}, journal={Glia}, year={1995}, volume={15 2}, pages={167-72} }