Evidence for contribution of tripartite hemolysin BL, phosphatidylcholine-preferring phospholipase C, and collagenase to virulence of Bacillus cereus endophthalmitis.

@article{Beecher2000EvidenceFC,
  title={Evidence for contribution of tripartite hemolysin BL, phosphatidylcholine-preferring phospholipase C, and collagenase to virulence of Bacillus cereus endophthalmitis.},
  author={Douglas J. Beecher and Timothy W. Olsen and Eileen B. Somers and Amy C. Lee Wong},
  journal={Infection and immunity},
  year={2000},
  volume={68 9},
  pages={
          5269-76
        }
}
Bacillus cereus causes a highly fulminant endophthalmitis which usually results in blindness. We previously concluded that hemolysin BL (HBL), a tripartite necrotizing pore-forming toxin, is a probable endophthalmitis virulence factor because it is highly toxic to retinal tissue in vitro and in vivo. We also determined that B. cereus produces additional retinal toxins that might contribute to virulence. Here we fractionated crude B. cereus culture supernatant by anion-exchange chromatography… CONTINUE READING

Citations

Publications citing this paper.
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  • International journal of food microbiology
  • 2008
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

The dangers of sublethal carvacrol exposure: increases in virulence of Bacillus cereus during endophthalmitis.

  • International journal of biochemistry and molecular biology
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Production and characterization of two hemolysins of Bacillus cereus.

  • Canadian journal of microbiology
  • 1978
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

Introduction to the family of the structurally related cholesterol - binding cytolysins ( ‘ sulfhydryl - activated ’ toxins )

J. E. Alouf
  • 1999

Introduction to the family of the structurally related cholesterol-binding cytolysins (‘sulfhydryl-activated

J. E. Alouf
  • toxins), p. 443–456
  • 1999
VIEW 1 EXCERPT