Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane.

@article{Chabowski2007EvidenceFC,
  title={Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane.},
  author={Adrian Chabowski and J. Cristopher Gorski and Joost J. F. P. Luiken and Jan F. C. Glatz and Arend Bonen},
  journal={Prostaglandins, leukotrienes, and essential fatty acids},
  year={2007},
  volume={77 5-6},
  pages={345-53}
}
There is substantial molecular, biochemical and physiologic evidence that long-chain fatty acid transport involves a protein-mediated process. A number of fatty acid transport proteins have been identified, and for unknown reasons, some of these are coexpressed in the same tissues. In muscle and heart FAT/CD36 and FABPpm appear to be key transporters. Both proteins are regulated acutely (within minutes) and chronically (hours to days) by selected physiologic stimuli (insulin, AMP kinase… CONTINUE READING