Evidence for calcium-sensing receptor mediated stanniocalcin secretion in fish.

@article{Radman2002EvidenceFC,
  title={Evidence for calcium-sensing receptor mediated stanniocalcin secretion in fish.},
  author={Dennis P Radman and Christopher R. McCudden and Kathi A. James and Edward M Nemeth and Graham F. Wagner},
  journal={Molecular and cellular endocrinology},
  year={2002},
  volume={186 1},
  pages={111-9}
}
The secretion of parathyroid hormone (PTH) and calcitonin (CT) in mammals are both tightly regulated by the prevailing levels of extracellular ionic calcium (Ca(2+)). And, it is now widely recognized that both of these Ca(2+) effects are mediated exclusively through a seven transmembrane calcium sensing receptor or CaR. As in the case of PTH and CT, the secretion of stanniocalcin (STC) in fish is tightly regulated by the levels of extracellular Ca(2+). Fish STC functions as an anti… CONTINUE READING

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