Evidence for apoptosis in non-small cell lung carcinoma. Relationship with cell kinetics and prognosis.

@article{Matturri1999EvidenceFA,
  title={Evidence for apoptosis in non-small cell lung carcinoma. Relationship with cell kinetics and prognosis.},
  author={Luigi Matturri and Barbara Colombo and Anna Maria Lavezzi},
  journal={Analytical and quantitative cytology and histology},
  year={1999},
  volume={21 3},
  pages={240-4}
}
OBJECTIVE To investigate cell death via apoptosis in non-small cell lung carcinoma (NSCLC) and its correlation with proliferative indices and follow-up. STUDY DESIGN In 38 cases of NSCLC (21 squamous cell carcinomas and 17 adenocarcinomas) we analyzed apoptosis by nuclear morphology and in situ DNA fragmentation end labeling and the cell kinetics by an autoradiographic method with tritiated thymidine and by immunohistochemistry with anti-proliferating cell nuclear antigen (anti-PCNA… CONTINUE READING