Evidence for apoptosis in human intracranial aneurysms.

  title={Evidence for apoptosis in human intracranial aneurysms.},
  author={Akira Hara and Naoki Yoshimi and Hiromu Mori},
  journal={Neurological research},
  volume={20 2},
There is no accepted hypothesis explaining the mechanism of growth and the subsequent rupture of intracranial aneurysms. Both congenital and acquired factors are believed to contribute to the formation and development of intracranial aneurysms. Apoptosis, commonly observed under a wide range of physiological conditions, occurs in the various pathological situations including some vascular diseases. We discuss the contribution of apoptosis to the formation and the rupture of human intracranial… CONTINUE READING