Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia.

@article{Clarke2009EvidenceFA,
  title={Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia.},
  author={Mary Clarke and Antti Tanskanen and Matti O. Huttunen and John C. Whittaker and Mary Cannon},
  journal={The American journal of psychiatry},
  year={2009},
  volume={166 9},
  pages={1025-30}
}
OBJECTIVE The authors sought to determine whether prenatal exposure to infection and a positive family history of psychotic disorders interact synergistically to increase the risk of later developing schizophrenia. METHOD The authors linked two national registers, the Medical Birth Register and the Finnish Population Register, to identify all women in Helsinki who received hospital treatment during pregnancy for an upper urinary tract infection (N=9,596) between 1947 and 1990. The Finnish… CONTINUE READING
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