Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms.

@article{Agrawal2009EvidenceFA,
  title={Evidence for an interaction between age at first drink and genetic influences on DSM-IV alcohol dependence symptoms.},
  author={Arpana Agrawal and Carolyn E Sartor and Michael T Lynskey and Julia D. Grant and Michele L. Pergadia and Richard A Grucza and Kathleen K Bucholz and Elliot C. Nelson and Pamela A. F. Madden and Nicholas G. Martin and Andrew C. Heath},
  journal={Alcoholism, clinical and experimental research},
  year={2009},
  volume={33 12},
  pages={
          2047-56
        }
}
BACKGROUND Research suggests that individuals who start drinking at an early age are more likely to subsequently develop alcohol dependence. Twin studies have demonstrated that the liability to age at first drink and to alcohol dependence are influenced by common genetic and environmental factors, however, age at first drink may also environmentally mediate increased risk for alcohol dependence. In this study, we examine whether age at first drink moderates genetic and environmental influences… CONTINUE READING

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