Evidence for an early endometrial response to pregnancy in cattle: both dependent upon and independent of interferon tau.

@article{Forde2012EvidenceFA,
  title={Evidence for an early endometrial response to pregnancy in cattle: both dependent upon and independent of interferon tau.},
  author={Niamh Forde and Gillian B. Duffy and Paul A. McGettigan and John A. Browne and Jai Prakash Mehta and Alan K. Kelly and Nadera Mansouri-Attia and Olivier Sandra and Brendan J. Loftus and Mark A. Crowe and Trudee Fair and James F. Roche and Pat Lonergan and A. C. O. Evans},
  journal={Physiological genomics},
  year={2012},
  volume={44 16},
  pages={
          799-810
        }
}
The aims of this study were to 1) identify the earliest transcriptional response of the bovine endometrium to the presence of the conceptus (using RNAseq), 2) investigate if these genes are regulated by interferon tau (IFNT) in vivo, and 3) determine if they are predictive of the pregnancy status of postpartum dairy cows. RNAseq identified 459 differentially expressed genes (DEGs) between pregnant and cyclic endometria on day 16. Quantitative real-time PCR analysis of selected genes revealed… Expand
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Title: Interferon tau-dependent and independent effects of the bovine conceptus on the endometrial transcriptome Running title: Bovine endometrial gene expression Summary sentence: Elongating bovine conceptuses modify the adjacent endometrial transcriptome in a manner dependent and independent of in
This study investigated bovine conceptus-induced modifications to the endometrial transcriptome related to effects of interferon tau (IFNT), conceptus origin (in vivo vs. in vitro) D ow naded romExpand
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