Evidence for an autocrine role of activin B within rat anterior pituitary cultures.

@article{Corrigan1991EvidenceFA,
  title={Evidence for an autocrine role of activin B within rat anterior pituitary cultures.},
  author={Anne Z. Corrigan and Louise M. Bilezikjian and Rona S. Carroll and Laura N. Bald and Christian E H Schmelzer and Brian M. Fendly and Anthony J. Mason and William Wei Lim Chin and R. H. Schwall and Wylie Vale},
  journal={Endocrinology},
  year={1991},
  volume={128 3},
  pages={1682-4}
}
Activins, dimers of inhibin beta subunits, are potent stimulators of FSH secretion in vivo and in vitro and of FSH beta mRNA expression in rat anterior pituitary cultures. In this study, we investigated the possibility that locally secreted activin B (beta B beta B) may function as an autocrine modulator of basal FSH secretion and expression based on the previous observation that beta B is expressed within gonadotropes. The incubation of cultured rat anterior pituitary cells with a m mouse… CONTINUE READING
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