Evidence for an ancestral alphoid domain on the long arm of human chromosome 2

@article{Avarello2004EvidenceFA,
  title={Evidence for an ancestral alphoid domain on the long arm of human chromosome 2},
  author={Rosamaria Avarello and Antonio Pedicini and Angela Caiulo and Orsetta Zuffardi and Marco Fraccaro},
  journal={Human Genetics},
  year={2004},
  volume={89},
  pages={247-249}
}
SummaryIn situ hybridization, under low stringency conditions with two alphoid DNA probes (pYα1 and p82H) labeled with digoxigenin-dUTP, decorated all the centromeres of the human karyotype. However, signals were also detected on the long arm of chromosome 2 at approximately q21.3–q22.1. Since it is supposed that human chromosome 2 originated by the telomeric fusion of two ancestral primate chromosomes, these findings indicate that not only the telomeric sequences, but also the ancestral… Expand
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