Evidence for an HLA-C-like locus in the orangutan Pongo pygmaeus

@article{Adams1999EvidenceFA,
  title={Evidence for an HLA-C-like locus in the orangutan Pongo pygmaeus},
  author={Erin J. Adams and G. Thomson and Peter Parham},
  journal={Immunogenetics},
  year={1999},
  volume={49},
  pages={865-871}
}
 HLA-B and C are related class I genes which are believed to have arisen by duplication of a common ancestor. Previous study showed the presence of orthologues for both HLA-B and C in African apes but only for HLA-B in Asian apes. These observations suggested that the primate C locus evolved subsequent to the divergence of the Pongidae and Hominidae. From an analysis of orangutan Tengku two HLA-C-like alleles (Popy C*0101 and Popy C*0201) were defined as well as three HLA-B-like (Popy-B… CONTINUE READING
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A theory of human and primate evolution

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  • 1989
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