Evidence for an Ancestral Association of Human Coronavirus 229E with Bats.

  title={Evidence for an Ancestral Association of Human Coronavirus 229E with Bats.},
  author={Victor Max Corman and Heather J Baldwin and Adriana Fumie Tateno and Rodrigo Melim Zerbinati and Augustina Angelina Annan and Michael Owusu and Evans Ewald Nkrumah and Gael Darren Maganga and Samuel Osei-Bonsu Oppong and Y Adu-sarkodie and Peter Vallo and Luiz Vicente Ribeiro Ferreira da Silva Filho and {\'E}ric Maurice Leroy and Volker Thiel and Lia van der Hoek and Leo L. M. Poon and Marco Tschapka and Christian Drosten and Jan Felix Drexler},
  journal={Journal of virology},
  volume={89 23},
UNLABELLED We previously showed that close relatives of human coronavirus 229E (HCoV-229E) exist in African bats. The small sample and limited genomic characterizations have prevented further analyses so far. Here, we tested 2,087 fecal specimens from 11 bat species sampled in Ghana for HCoV-229E-related viruses by reverse transcription-PCR (RT-PCR). Only hipposiderid bats tested positive. To compare the genetic diversity of bat viruses and HCoV-229E, we tested historical isolates and… CONTINUE READING
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