Evidence for altered anorectal function in irritable bowel syndrome patients with sleep disturbance.

@article{Chen2011EvidenceFA,
  title={Evidence for altered anorectal function in irritable bowel syndrome patients with sleep disturbance.},
  author={C L Chen and Tso-Tsai Liu and Chih-Hsun Yi and William C. Orr},
  journal={Digestion},
  year={2011},
  volume={84 3},
  pages={247-51}
}
BACKGROUND/AIMS Sleep dysfunction is associated with altered gastrointestinal functioning and the presence of irritable bowel syndrome (IBS). We aimed to investigate whether sleep dysfunction would influence anorectal motility in IBS patients. METHODS A total of 16 healthy volunteers and 15 IBS patients underwent anorectal manometry. The anorectal parameters included resting and squeeze sphincter pressure, sensory thresholds in response to balloon distension, and rectoanal inhibitory reflex… CONTINUE READING