Evidence for a significant role of CD4+ T cells in adoptive immunity to Listeria monocytogenes in the liver.

@article{Rakhmilevich1994EvidenceFA,
  title={Evidence for a significant role of CD4+ T cells in adoptive immunity to Listeria monocytogenes in the liver.},
  author={Alexander L. Rakhmilevich},
  journal={Immunology},
  year={1994},
  volume={82 2},
  pages={
          249-54
        }
}
Although the ability of CD8+ T cells to adoptively immunize mice against Listeria monocytogenes in the spleen is well established, the role of different T-cell subsets in anti-bacterial protection in the liver, a major target of Listeria infection, remains unclear. Therefore, the ability of sorted CD4+ and CD8+ T cells to adoptively immunize mice against a L. monocytogenes infection in the liver was studied. The results show that positively sorted CD4+ T cells from day 7 Listeria-immune mice… CONTINUE READING
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