Evidence for a role of vasopressin in the control of aldosterone secretion in primary aldosteronism: in vitro and in vivo studies.

@article{Perraudin2006EvidenceFA,
  title={Evidence for a role of vasopressin in the control of aldosterone secretion in primary aldosteronism: in vitro and in vivo studies.},
  author={V{\'e}ronique Perraudin and Catherine Delarue and Herv{\'e} Pierre Lefebvre and Jean-Luc Do Rego and Hubert Vaudry and J W Kuhn},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 4},
  pages={1566-72}
}
CONTEXT Arginine vasopressin (AVP) stimulates steroid secretion from the normal human adrenal gland and some cortisol-producing adrenocortical tumors or hyperplasia through activation of the V(1a) receptor. OBJECTIVE The objective of the study was to investigate in vitro and in vivo the possible involvement of AVP in the physiopathology of primary aldosteronism. DESIGN The design of the study included immunohistochemical, pharmacological, and molecular studies on aldosterone-producing… CONTINUE READING

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