Evidence for a role of the N terminus and leucine-rich repeat region of the Mi gene product in regulation of localized cell death.

@article{Hwang2000EvidenceFA,
  title={Evidence for a role of the N terminus and leucine-rich repeat region of the Mi gene product in regulation of localized cell death.},
  author={C F Hwang and Amrita Bhakta and Gina M. Truesdell and W M Pudlo and V. Williamson},
  journal={The Plant cell},
  year={2000},
  volume={12 8},
  pages={1319-29}
}
The tomato Mi gene confers resistance against root-knot nematodes and potato aphids. Chimeric constructs of the functional gene, Mi-1. 2, with a homolog, Mi-1.1, were produced, and their phenotypes were examined in Agrobacterium rhizogenes-transformed roots. Exchange of the leucine-rich repeat (LRR) region of Mi-1.1 into Mi-1.2 resulted in the loss of ability to confer nematode resistance, as did substitution of a 6-amino acid sequence from the Mi-1.1 LRR into Mi-1.2. Introduction of the Mi-1.2… CONTINUE READING

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