Evidence for a role of opioid peptides in the release of arginine vasopressin in the conscious rat.

@article{Ishikawa1982EvidenceFA,
  title={Evidence for a role of opioid peptides in the release of arginine vasopressin in the conscious rat.},
  author={S. Ishikawa and R. Schrier},
  journal={The Journal of clinical investigation},
  year={1982},
  volume={69 3},
  pages={
          666-72
        }
}
  • S. Ishikawa, R. Schrier
  • Published 1982
  • Medicine
  • The Journal of clinical investigation
  • Recent reports have suggested that opioid peptides may be involved in renal water excretion. The present in vivo experiments, therefore, were undertaken to determine the effect of opioid peptides on the osmotic and nonosmotic release of arginine vasopressin (AVP) in the conscious rat. Experimental animals were infused intravenously with naloxone (20 mug/kg per min) or oxilorphan (40 mug/kg per min), chemically dissimilar opioid antagonists. Control rats were infused with normal saline, the… CONTINUE READING
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