Evidence for a role for apoptosis in central pontine myelinolysis

@article{DeLuca2002EvidenceFA,
  title={Evidence for a role for apoptosis in central pontine myelinolysis},
  author={G C DeLuca and Zsuzsanna Nagy and Margaret M. Esiri and P Davey},
  journal={Acta Neuropathologica},
  year={2002},
  volume={103},
  pages={590-598}
}
  • G C DeLuca, Zsuzsanna Nagy, +1 author P Davey
  • Published in Acta Neuropathologica 2002
  • Medicine, Biology
  • Abstract. We have performed an immunocytochemical study of autopsy material from five cases of central pontine myelinolysis (CPM) and five age and sex-matched control subjects with the aim of exploring the possible involvement of apoptotic mechanisms in oligodendrocytes in this condition. We searched for immunoreactivity of glial cells for the apoptotic-related markers death receptor (DR) 3, Bax and Bak, the anti-apoptotic marker Bcl-2 and the cell cycle marker Ki-67. The latter marker was… CONTINUE READING

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