Evidence for a postsynthetic proteolytic transformation of human erythrocyte pyruvate kinase into L-type enzyme.

@article{Marie1977EvidenceFA,
  title={Evidence for a postsynthetic proteolytic transformation of human erythrocyte pyruvate kinase into L-type enzyme.},
  author={Joelle Marie and H. Garreau and Axel Kahn},
  journal={FEBS letters},
  year={1977},
  volume={78 1},
  pages={91-4}
}
The relationship between liver (L-type) and erythrocyte pyruvate kinase remains a subject of discussion. It has been previously demonstrated that these enzymes are kinetically [ 1,2] and immunologltally [3-51 related. In some cases liver (Ltype) pyruvate kinase from patients with hereditary erythrocyte pyruvate kinase deficiency was shown to be defective [2,6-81. Erythrocyte and L-type enzymes, however, can be distinguished by their electrophoretic mobilities [2,9] . Some authors [9] have… CONTINUE READING

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Enzyme in press. Beutler, E

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