Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord.

@article{Tahtouh2009EvidenceFA,
  title={Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord.},
  author={Muriel Tahtouh and Françoise Croq and Jacopo Vizioli and P S{\'a}uti{\`e}re and Christelle Van Camp and Michel Salzet and Mohamed R. Daha and J{\"o}el Pestel and Christophe Lefebvre},
  journal={Molecular immunology},
  year={2009},
  volume={46 4},
  pages={523-31}
}
In vertebrates, central nervous system (CNS) protection is dependent on many immune cells including microglial cells. Indeed, activated microglial cells are involved in neuroinflammation mechanisms by interacting with numerous immune factors. Unlike vertebrates, some lophotrochozoan invertebrates can fully repair their CNS following injury. In the medicinal leech Hirudo medicinalis, the recruitment of microglial cells at the lesion site is essential for sprouting of injured axons. Interestingly… CONTINUE READING

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