Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder.

@article{Nurnberger2001EvidenceFA,
  title={Evidence for a locus on chromosome 1 that influences vulnerability to alcoholism and affective disorder.},
  author={John J I Nurnberger and Tatiana Foroud and Leah Flury and Jessica A Su and Eric T. Meyer and K Hu and Ray Crowe and Howard J. Edenberg and Alison M. Goate and Laura J. Bierut and Theodore Reich and Marc I Schuckit and Wendy C Reich},
  journal={The American journal of psychiatry},
  year={2001},
  volume={158 5},
  pages={718-24}
}
OBJECTIVE Depression (major depression or depressive syndrome) is more prevalent in alcoholic than in nonalcoholic subjects in families with multiple members with alcoholism studied as part of the Collaborative Study on the Genetics of Alcoholism (National Institute on Alcohol Abuse and Alcoholism). First-degree relatives of probands with comorbid… CONTINUE READING