Evidence for a humoral factor (or factors) concerned in recovery from radiation injury: a review.

Abstract

The death of animals exposed to single totalbody doses of ionizing radiations in the lethal range is assumed to be due to the failure of func tional reconstitution of one or more of the tissues in the body (e.g., the hematopoietic system), and until recently the possibility of a specific approach to the management of the severe injury produced by such an exposure seemed far-fetched. Prophylactic measures, such as pretreatment with estrogen (53) or cysteine (43), have been used to reduce radiation morbidity and mortality in experimental animals, but, while of great funda mental importance, they are not effective in en hancing recovery when given after the radiation exposure has been sustained. Experiments which may be termed "therapeutic approaches" to the

Cite this paper

@article{Jacobson1952EvidenceFA, title={Evidence for a humoral factor (or factors) concerned in recovery from radiation injury: a review.}, author={Larry Jacobson}, journal={Cancer research}, year={1952}, volume={12 5}, pages={315-25} }