Evidence for a compensatory increase in synthesis of brush border enzymes in the jejunum of Irish Setters with gluten-sensitive enteropathy.

OBJECTIVE To determine whether biosynthesis of aminopeptidase N (ApN), alkaline phosphatase (AP), and total microvillus membrane protein is altered in Irish Setters with gluten-sensitive enteropathy (GSE). ANIMALS A litter of 6 Irish Setters with GSE and 3 healthy Greyhounds. PROCEDURES Explants obtained from affected dogs at 4 and 12 months were… CONTINUE READING