Evidence for a cholinergic projection to neocortex from neurons in basal forebrain.

Abstract

Unilateral stereotaxic injection of 3.5 nmol of kainic acid into the ventral globus pallidus of rats reduced biochemical cholinergic neuronal markers by 45-50% and virtually eliminated histochemical staining for acetylcholinesterase in neocortex ipsilateral to the lesion. At the lesion site, the large, multipolar neurons that stain densely for… (More)

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Cite this paper

@article{Johnston1979EvidenceFA, title={Evidence for a cholinergic projection to neocortex from neurons in basal forebrain.}, author={Michael V Johnston and Michael Mckinney and Joseph T Coyle}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1979}, volume={76 10}, pages={5392-6} }